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In these reactions GSH is oxidized to GSSG and the ratio [GSH]/[GSSG], an indicator of the redox status of the cell, is known to regulate redox sensitive enzymes in the pathways for cell proliferation and cell apoptosis [5]

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Aging: Natural production typically begins to taper off once we hit our 20s and 30s, leaving us with less of a buffer against oxidative stress as the years go on