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Over periods ranging from 1 to 4 years, no significant hepatotoxicity was observed, and incidences of ALT and AST elevations greater than three times the upper limit of normal (ULN) were rare

Numerous dietary phytochemicals are helpful in primary chemoprevention since it has been found that they suppress the initiation phase of carcinogenesis

Glutathione supplementation is not automatically recommended , but may be considered after 3 months postpartum with doctor approval

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Epilepsia 48 , 505516 (2007)

For example, a clinical trial involving TXNRD1 inhibitor auranofin has been enrolled in phase I/II clinical trials to treat chronic lymphocytic leukemia, non-small cell lung cancer, and ovarian, peritoneal, and fallopian tube cancers (www.clinicaltrials.gov, trial numbers NCT01419691, NCT01737502, NCT01747798, and NCT03456700)