The most commonly reported ones include: Rashes: Red, inflamed areas on the skin that can be itchy or uncomfortable
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To identify and prioritize responsive cell populations over time and treatment, we annotated differentially abundant sub-populations of cells using to Milo tool 38
Damaged AECs release pro-inflammatory and pro-fibrotic mediators, including interleukin (IL) -1 and tumor necrosis factor (TNF) -, which promote fibroblast recruitment, inflammatory cell activation (e.g., neutrophils, Th17, gdT cells), and myofibroblast differentiation, ultimately leading to ECM accumulation and fibrotic tissue remodeling [20, 29, 33, 34]
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Schneider, A