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Vitamin B12 can interact with medications such as colchicine (a medicine used to treat gout), metformin (an anti-diabetic agent), excessive alcohol, vitamin C products, extended release potassium products, antibiotics such as gentamicin, neomycin, tobramycin, anti-seizure medications such as phenobarbital, phenytoin, primidone, medicines used to treat heartburn like H2 blockers such as cimetidine and proton pump inhibitors such as omeprazole, antacids such as ranitidine, cimetidine

Preclinical studies show accelerated tendon healing, enhanced collagen synthesis, and improved biomechanical outcomes in animal models