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PMC 9794587

Indications: Overactive bladder Common symptoms include urgency, urinary incontinence, and increased urinary frequency Side Effects: increased blood pressure / hypertension urinary tract infections nasopharyngitis constipation Pharmacokinetics: taken orally by tablet, 25 mg once daily metabolized via multiple pathways involving dealkylation, oxidation, glucuronidation, and hydrolysis 6-12% is eliminated unchanged by the kidney, involving glomerular filtration and active secretion that is dose-dependent Drug Interactions: mirabegron is a moderate inhibitor of CYP2D6 Notes: the estimated Walmart cost for Mybetriq oral 50mg tablets is ~$440 for a supply of 30 tablets (GoodRx.com

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Selective decontamination of the digestive tract: concept and application

Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: role of intracellular calcium and nitric oxide

Brain Res Bull 166:172184 Wang X, Hu Z, Zhong K (2021b) The role of brain-derived neurotrophic factor in Epileptogenesis: an update