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10.1016/j.taap.2022.116215 23 LiuJ.XiaoQ.XiaoJ.NiuC.LiY.ZhangX.et al (2022)

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Patients who were already treated with NPH insulin either continued on the same total daily NPH insulin dose or started LANTUS at a dosage that was 80% of the total previous NPH insulin dosage

From a public health perspective, these transformations are beneficial for weight loss, blood sugar control and cardiovascular outcomes

Figure 3 Figure 4 shows the total risk of fracture of each therapy compared with other therapies

These figures describe the published literature, not recommended human applications