Written by: Ed Cooper Written on: April 24, 2026 Human biologist and longevity expert Gary Brecka has spent over two decades at the sharp end of functional medicine and biohacking, advising everyone from high-performing CEOs to next-gen professional athletes around the world on the most effective, cutting-edge ways to optimise their health
Fatigue: Paradoxical tiredness initially, due to metabolic adjustments
By stimulating glutathione levels, it has a positive effect on insulin secretion and increases insulin sensitivity, so it can be used as an adjunct in the treatment of insulin-resistant conditions in polycystic ovary syndrome, which is closely related to insulin resistance (13)
Finding the right dose of Zepbound is a personalized process that balances effectiveness and side effects
overexertion, increased fatigue, exhaustion
PSD-95, the increased expression of which at synapses is critical for persistent spine enlargement (Meyer et al., 2014), may also act as a positive PRP