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Numerous hypotheses have been posited to elucidate the genesis of pruritus, albeit none deemed definitive

When stored properly at -20C in a sealed container away from direct light and moisture, lyophilized GHK-Cu remains stable for 24-36 months from the date of manufacture

Some studies also indicated a beneficial role for Se supplementation, but there is insufficient evidence

A 2025 systematic review confirmed that probiotic supplementation in T2DM patients leads to a significant elevation in total antioxidant capacity (TAC) and a reduction in malondialdehyde (MDA), a marker of lipid peroxidation (442, 443)

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