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Antioxidant and neuroprotective markers in vitro work has tracked changes in lipid peroxidation, free-radical markers and cellular stress response in DSIP-exposed neural tissue

MAO-B MAO-B (Monoamine Oxidase B) is highly and selectively expressed in astrocytes, and its upregulation in reactive states exhibits greater astrocyte specificity than that of TSPO

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RA patients also showed increased levels of 2-aminoheptanoic acid, 2-aminooctanoic acid, 2-hydroxypyridine, shikimate, s-ribosyl-homocysteine, and phenylalanine and also decrease in deoxy carnitine, cystathionine involved in methylation, and lactate

Notably, supplementation with cholesterol in vitro corrects Scap deficiency-associated defects in cell proliferation and metabolism

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