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In a recent study, it has been demonstrated that tyrosine kinase inhibitor (TKI) resistance in non-small cell lung cancer (NSCLC) could be caused by mutated epidermal growth factor receptor (EGFR) which uses the regulation of the fatty acid synthase (FASN) to induce TKI [134]

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In addition, the activity of erastin and RSL3 has been used as a single or combined therapy for prostate cancer [133]