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Additionally, Huanglian-Banxia (HL-BX) Decoction regulates brain-gut neurotransmitters via the MAPK signaling pathway, reducing food intake while accelerating gastric emptying and increasing body weight, making it a promising treatment for diabetic gastroparesis (Tian et al., 2024)

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Tirzepatide's dual GLP-1/GIP mechanism activates an additional appetite-suppression pathway, often producing results for patients who plateaued on semaglutide

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