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Competing interests No

GLP-1 is a natural hormone released from the gut that ultimately sends a signal to the liver, telling it to stop dumping sugar into the bloodstream (in this way it shares a similar therapeutic action to Metformin)

EllieMD Other Your Next Chapter in 3 Simple Steps Tell us about your preferences, goals, and health to see if Dihexa is right for you

You should contact your GP or clinical trial team if cold sensations are persistent or accompanied by fatigue, pallor, shortness of breath, hair loss, or colour changes in your fingers and toes, as these may indicate anaemia, thyroid dysfunction, or Raynaud's phenomenon requiring investigation

Common short-term side effects include gastrointestinal discomfort that typically improves with dose titration, while longer-term safety monitoring focuses on metabolic markers, gallbladder disease signals, and rare adverse events identified in post-marketing surveillance

PlexusDx Compounded Semaglutide Delivery and Storage Setup PlexusDx ships compounded semaglutide injections in thermally insulated packaging with temperature-monitoring data loggers to ensure arrival in perfect condition