NNMT inhibition significantly increases energy expenditure, reduces body weight and white adipose mass, and improves insulin sensitivity
Keep in mind, the results arent permanent
The presence of previous neurological damage from B12 deficiency may necessitate more frequent injections to prevent symptom recurrence, even after initial improvement
The main rationale for cycling rather than continuous use involves conservative safety practices given limited long-term human data, cost management, and theoretical concerns about receptor desensitization with extended exposure
This is the more commonly recommended option, and for good reason
For conditions where runaway inflammation is the dominant pathology ulcerative colitis at a cellular level, for example BPC-157 alone may not fully address the inflammatory mechanism