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In some cases, surgical removal of the gallbladder (cholecystectomy) is required

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Signs and Symptoms of Hemorrhoids Internal Prolapsed External Swelling around the anus Itching or irritation in the anal region Discomfort or pain Bleeding Thrombosed Swelling Severe pain A discolored, hard lump near the anus Inflammation Hemorrhoid Causes and Risk Factors Consuming a low-fiber diet Pushing hard to have a bowel movement Pregnancy Engaging in anal intercourse Being overweight or obese Chronic constipation or diarrhea Straining when weight lifting or lifting heavy objects Sitting on the toilet for long periods of time A family history of hemorrhoids Rectal surgery Spinal injury A sedentary lifestyle Inflammatory bowel disease (IBD) Aging Hemorrhoid Diagnosis Treatment Options for Hemorrhoids Fortunately, most hemorrhoids can be treated at home or with simple medical procedures in a doctors office

Diabetes Obes Metab 4:329335 Yasuda N, Inoue T, Nagakura T et al (2002) Enhanced secretion of glucagon-like peptide 1 by biguanide compounds