Pooled effect sizes indicated that receiving GLP-1 receptor agonists did not cause a statistically significant change in serum TG (WMD = 7.07, 95% CI = [17.51, 3.37], P =0.18), TC (WMD = 1.17, 95% CI = [5.25, 2.91], P =0.57), HDL-C (WMD = 0.97, 95% CI = [1.63, 3.58], P =0.46), and LDL-C (WMD = 1.67, 95% CI = [10.08, 6.74], P =0.69) in comparison with controls
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IGF-1 LR3 delivers direct, potent IGF-1 receptor activation with extended half-life enabling once-daily administration, but lacks HGHs additional metabolic effects