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Though the antioxidant capacity of Lip-1 is well established [103], researchers have also implicated NRF2 upregulation [106], LPCAT3 and 15-LOX inhibition [107], and GPX4 and GSH upregulation [100] as core mechanisms of radioprotection by Lip-1

In addition, several studies reported concentration-dependent cellular or BBB uptake of the developed compounds providing the data on the MichaelisMenten transport kinetic parameters (Table II)

In: Narayanan, A.S., Dharumadurai, D

10.3390/IJMS21228637 166 SchmidlinC

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