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Martin Whyte, an associate professor of metabolic medicine at the University of Surrey, explains one possible theory as to why people tend to regain weight after they stop these medications

Focus on progressive overload where possible

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It is approved for weight management in adults and pediatric patients 12 years and older with obesity, as well as adults with overweight who have at least one weight-related health condition

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In addition, it can also activate the UCP1 protein in brown adipose tissue (BAT), increase heat production, and achieve a transition from "energy wasting" metabolism (such as shivering heat production) to "efficient utilization" metabolism