That's the typical pathway for this demographic: topical exposure first, then discovery of systemic protocols, then a clinical consultation to make sense of the gap between the two
Account for this by adding 0.1-0.2 mL extra bacteriostatic water during reconstitution, or simply accept that the last draw from a vial may be slightly less than intended
Daily doses of 1,000 mcg have been reported as necessary in many cases to accommodate a wide range of Vitamin B12 use and storage in different people
Vitamin B12 is important for brain function, and a deficiency can lead to cognitive impairment, such as memory loss and difficulty concentrating
Adverse Reactions/Side Effects Mild transient diarrhea, polycythemia vera, peripheral vascular thrombosis, itching transitory exanthema, feeling of swelling of entire body, anaphylactic shock and death
doi: 10.3389/fendo.2021.645617 Received 23 December 2020 Accepted 08 March 2021 Published 25 June 2021 Volume 12 - 2021 Edited by Gaetano Santulli, Columbia University, United States Reviewed by Bo Ahrn, Lund University, Sweden