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[ 14 C]-Metformin uptake was 13 times higher in OCT3-BT20 cells than in BT-20 cells, and associated with increased AMPK phosphorylation and decreased pS6K phosphorylation in OCT3-BT20 cells and these results were substantiated in mice with OCT3 overexpressing tumors (241)

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Other exclusion criteria included components like alcohol consumption over a certain amount and use of GLP-1 receptor agonists in the three months leading up to screening

J CLin Endocrinol Metab