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Polydatin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation by inhibiting NF-B/NLRP3 inflammasome activation via the AMPK/SIRT1 pathway

95% CI 0.730.8) [34]

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Efpeglenatide is a drug in which an exendin-4 analog is linked to a human immunoglobulin G4 fragment through a polyethylene glycol (PEG linker), allowing for Fc receptor of neonate (FcRn)-mediated recycling and reduced excretion through the kidneys [50]

Gastrointestinal side effects such as nausea and vomiting, common during treatment initiation, may further compromise nutritional status