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10.1016/j.pharmthera.2019.05.010 55 WangQ.YuS.SimonyiA.RottinghausG.SunG

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Consumption of raw or wild foods by non-urbanized populations, for example, the Hadza community, results in a more diverse gut ecosystem, compared to urban populations that primarily consume a diet consisting of commercial or processed agricultural food products (Schnorr et al., 2014

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Hemin suppresses the TSS pathway CBS expression and interferes with de novo cysteine biosynthesis and GSH generation, leading to elevated oxidative stress