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An important model to study the consequences of systemic carnitine deficiency is the homozygous OCTN2 null mouse, in which OCTN2 function is abolished by the missense mutation L352R

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Thats exactly what has happened here, and both plan sponsors and pharmacy benefit managers (PBMs) have been trying to figure out how to manage the growing demand

This approach could identify patients with documented symptoms who have not received appropriate evaluation or diagnosis (Chen et al., 2020)

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