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Cortisol spikes will cause them to hold water, making them look bloated and puffy

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What NAPQI does: Directly binds to and damages cellular proteins Depletes glutathione rapidly Generates oxidative stress which damages DNA Triggers cell death Damages mitochondria, disrupting energy production NAPQI crosses the placenta and depletes fetal brain glutathione at doses below those causing maternal liver toxicity

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Here are a few more: Trigonelline Deterpenes such as cafestol and kahweol Polyphenols including chlorogenic acids, caffeic acid, and other free radical reducing compounds Magnesium up to 7mg per cup