It covers the same places, but may have larger groups, simpler food, fewer comforts, or shared transportation
No conclusions regarding safety, efficacy, or application outside of controlled research environments should be inferred
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Adverse effects observed in trials to date include: Gastrointestinal symptoms nausea, vomiting, diarrhoea, and constipation (common with GLP-1 receptor agonists) Reduced appetite and weight loss , which may be excessive in some individuals Elevated heart rate , a concern noted with glucagon receptor agonism As with other incretin-based therapies, there is also a class-level signal for acute pancreatitis and gallbladder disease (including cholelithiasis and cholecystitis)
For instance, while Haggarty [18] found no direct association, our analysis of non-linear relationships uncovered a significant threshold effect
