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In vivo functional profiling and structural characterization of the human GLP1R A316T variant
and one 1-year, open-label trial that included 12 pediatric patients with POMC or LEPR deficiency or BBS aged 2 to less than 6 years (Trial 5) [see Clinical Studies (14.2, 14.3, 14.4)]
It describes stability testing that evaluates how the compound performs under defined storage conditions and identifies the point at which potency falls below acceptable therapeutic levels
Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
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