Both use bacteriostatic water as the standard diluent
AQ undergoes rapid and extensive hepatic metabolism to its pharmacologically active metabolite DEAQ, predominantly by cytochrome P450 2C8 (CYP2C8) (Li et al., 2002)
Studies also found that LC and ALC can reduce neurotoxicity caused by mitochondrial dysfunction, such as uncoupling or oxidative phosphorylation inhibition [38, 39]
Although bubbling under N 2 gas has been reported to reduce soluble O 2 [35], NAC and diNAC content remained comparable to samples stored without N 2 purging (Supplementary Fig
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For example, in human PAECs under hypoxic conditions, the levels of ROS were increased, while the levels of mitochondrial thioredoxin 2, an antioxidant protein, were reduced which could contribute to exacerbating hypoxia-induced ROS production [157]