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A phase I safety study in healthy adults confirmed that subcutaneous MOTS-c injections at doses up to 10 mg produced no serious adverse events, with a pharmacokinetic profile supporting once-daily or every-other-day dosing [3]

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But, more than this, the experts were clear that not only are the supplements not tested in the same way as the drugs, but they're largely unregulated, meaning you can't be sure what's actually in them

FEBS Letters 584 (2010) 29212925.

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Side effects of ipamorelin are generally mild but can include slight water retention, headaches, or redness at the injection site