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[3] Report any suspected side effects via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)

Reduce Insulin Resistance: Metformin (biguanide) and thiazolidinediones (TZDs) improve insulin sensitivity in the liver, muscle, and adipose tissue

The 1 mg/mL concentration maxes out a standard U-100 syringe at this dose, which is one practical reason providers prefer higher concentrations for maintenance phases

Hunger, Temptation, and Dietary Adherence During Weight Management