In the circulation, the reduced form of homocysteine results from a direct cellular efflux (Blom, 2000) or from circulating thiolactone hydrolysis by homocysteine thiolactone hydrolase (Jakubowski, 2000b)
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et al (2023)
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Toxicity evaluation According to a patent, "Short duration safety studies with Dihexa have uncovered no apparent toxicity