Supplements with polypodium & glutathione can potentially be helpful in other pigmentary disorders including- Ashy dermatosis Lichen planus Drug eruptions (photosensitive) Endocrine pigmentary disorders Vitiligo What other vitamins can treat melasma
Dosage & Administration ['Adults: 1 effervescent tablet in 200 ml water once daily', 'Drink immediately after dissolving', 'Take on an empty stomach for best absorption', 'Continue for 812 weeks'] Side Effects ['Generally well tolerated', 'Mild GI upset', 'Allergic reaction (rare)', 'Sulfurous taste in some patients'] Contraindications & Precautions ['Hypersensitivity to glutathione or vitamin C', 'G6PD deficiency (caution)', 'Active peptic ulcer'] Storage Store below 25C, keep bottle tightly closed
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Djokic G, Vojvodi P, Korcok D, et al
Biochem J 2009
5B, the expression level of ovarian DNMT3a in the PCOS-induced rats was 50% greater than the control group ( P 0.05) (Fig