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mTORmechanistic target of rapamycin
## Combining Semaglutide with Supportive Therapies One advantage of transitioning from AOD-9604 to a GLP-1 **weight loss peptide** is the ability to complement the protocol with well-studied supportive therapies: ### NAD+ for Metabolic and Anti-Aging Support [NAD+ injections](/guides/nad-injection-benefits-anti-aging-energy-recovery-guide) support mitochondrial function, cellular energy production, and DNA repair all of which may be beneficial during active **fat loss**
The achieved effect depends, among others, on environmental factors such as pH, the presence of salt or the presence of substances that can change the hydrophobicity of the peptide (Kandasamy and Larson, 2006)
Its safety profile was statistically indistinguishable from placebo on all measured parameters
Some individuals report lightning effects in areas of hyperpigmentation, but results vary and require medical supervision
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