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Diabetes, obesity and gut microbiota

This is demonstrated clinically as raising HDL levels through injections of reconstituted HDL (rHDL) resulted in atherosclerotic plaque regression, as determined by intravascular ultrasound (728)

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So, pharmaceutical companies started investigating the use of GLP-1s for weight-management purposes, and the first GLP-1 weight-loss drug, Saxenda (liraglutide), was approved by FDA in 2014 (it was previously approved to treat diabetes under the name Victoza)