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Special attention was placed on comparison of EtOH-treated mice with time-matched controls, to account for the decreases in GSH resulting from food deprivation [34]

Fang found that in the myocardium of mice specifically deficient in ferritin H (Fth), iron levels decreased, and oxidation levels increased, resulting in mild cardiac aging damage

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LONP1 specifically recognizes and degrades misfolded proteins, oxidatively damaged proteins, protein aggregates, and some critical proteins related to mitochondrial function, thereby maintaining mitochondrial protein homeostasis

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