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The Week 72 analysis included 800 F2 and F3 (at eligibility) patients randomized 1:2 to receive placebo (n=266) or WEGOVY once weekly (n=534), in addition to standard of care for cardiometabolic comorbidities and healthy lifestyle counseling
It helps prevent fatty liver disease and supports the metabolism of cholesterol
However, future time-course studies with a larger sample size are needed to elucidate the dynamic changes in composition and diversity of commensal microbiomes, and the inclusion of pathobionts in the whole respiratory system and gut during the progression of COVID-19
GLP-1RAs and DPP-4is have been compared in patients with fair kidney function in previous studies, which have reported a decrease in HbA1c [23,24,25] and reduction in body weight [25]
It is only prescribed for about 12 weeks