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Moreover, genetic screening can allow physicians to better identify patients at greater risk of adverse effects from specific medications, thus avoiding unnecessary treatments

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Regulatory approval and reimbursement require prospective evidence that biomarker-guided decisions improve patient-centred outcomes and demonstrate cost-effectiveness, and such evidence remains limited for most candidate signatures [483, 486]

Vegetarians and vegans Vitamin B12 recommendations do not differ for people following a plant-based diet

[11] It is less preferred than hydroxocobalamin for treating vitamin B 12 deficiency because it has a slightly lower bioavailability

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