This ensures the pen is working correctly and removes any air bubbles
Once those subcutaneous fat compartments fill up, wherever they may be, fat will bury itself deeper in the body in the midsection, around your organs
2022 Jul 21;387(3):205-216
The rationale is that smaller individual doses may reduce GI side effects while maintaining the same total weekly exposure
Source: Zepbound (tirzepatide) Prescribing Information FDA Tirzepatide Side Effects Adverse events in the SURPASS (type 2 diabetes) and SURMOUNT (weight management) trials, summarised on the Mounjaro and Zepbound FDA prescribing labels, are predominantly gastrointestinal and most common during dose escalation
They can reduce gallbladder contraction and gastrointestinal motility, which could lead to cholecystitis and stomach paralysis (gastroparesis), a condition disrupting food movement from the stomach to the intestine