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Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1-mediated lipogenesis

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As more research emerges, understanding of GLP-1 receptor agonists continues to grow and Professor Badve likens them to the ACE inhibitors which similarly underwent a broadening of their list of indications over time

GGT1 overexpression enhanced SLC7A11 and GPX4 expression while suppressing ACSL4, thereby reducing lipid peroxidation, mitigating oxidative stress, and alleviating tubular injury, whereas co-silencing GCLC attenuated these protective effects

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