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Gene expression studies reveal modulation of 408 neuronal genes, including dramatic increases in OPRM1 (opioid receptor, up 1,294%), KCND1 (up 845%), and SLC8A2 (up 737%)

Mechanisms may involve enhancement of follicle stem cell activity, improvement of follicle vascularization, and anti-inflammatory effects on the follicle microenvironment

These channels appear to play a role in regulating neuronal excitability and are found in brain regions such as the hippocampus, amygdala, and prefrontal cortex

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