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The 5 mg group achieved a mean weight loss of 15% at 72 weeks

Roughly 30-40% of tirzepatide patients experience nausea significant enough to request an anti-nausea prescription during the first 8 weeks (Jastreboff et al., NEJM 2022)

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Individual responses vary, and practitioners often adjust based on symptom improvement and laboratory markers

Some patients feel fuller sooner and snack less often