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The SURPASS-2 trial (N=1,879) compared tirzepatide to semaglutide 1 mg and found tirzepatide 15 mg achieved an A1C reduction of 2.46% versus 1.86% with semaglutide 1 mg 10

Plan the dose to fall shortly before a meal, matching how the trials timed exposure to dietary antigens

Free Radic Res

It is not known whether this risk applies to humans, but Saxenda is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Used alongside healthy meals, activity, and expert monitoring

Illinois allows telehealth prescribing by licensed providers