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In studies and clinical discussions of GH/IGF-1 physiology, higher IGF-1 is associated with improved nitrogen balance and support for lean tissue maintenance, which may help body recomposition when paired with adequate protein intake and resistance training

Wilbon SS, Kolonin MG

Its worth pointing this out because so many people take anti-depressants (usually of the SSRI class) which may be making weight loss very difficult

Your skin has cells called fibroblasts

The most evidence-backed detox supplements for liver support are milk thistle (silymarin), N-acetylcysteine (NAC), and glutathione