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One study showed treating shock with methylene blue significantly shortened the time it took to reverse the effects of shock and shortened the length of stay in the intensive care unit

For a 250-pound person, that represents 50 or more pounds, results that were previously achievable only through bariatric surgery

There's simply less for it to work on

Wang X, Wu Q, Zhong M, Chen Y, Wang Y, Li X, Zhao W, Ge C, Wang X, Yu Y, et al

Bone mineral density in children and adolescents with Prader-Willi syndrome: a longitudinal study during puberty and 9 years of growth hormone treatment

Their abundance under inflammatory conditions enhances their appeal as therapeutic targets, especially through interactions with intercellular adhesion molecule 1