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Conformational effects of Gly-X-Gly interruptions in the collagen triple helix

Drugs and Clin

This is not medical advice and does not replace care from a qualified clinician

CrucianiRADvorkinEHomelPCullineyBMalamudSShaiovaLet al

The mechanism involves decreasing glucose reabsorption in the nephrons proximal tubule (via inhibition of the sodium-glucose linked cotransporter-2 protein)