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In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain

Immunol Lett (2010) 127(2):1506

For example, the sensitization of TRPA1 with a low dose exposure to acrolein causes sensitization of TRPV1 against capsaicin.[ref] Studies in workplaces that have high VOC levels show that TRPA1 activation is the molecular initial event (MIE) leading to sensory irritation.[ref] A 2022 study investigated the sensitivity to capsaicin, a TRPV1 receptor activator, in people with MCS compared to a control group

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So does the question of effectiveness