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The researchers included 30 obese patients in a randomized, double-blind, placebo-controlled, two-period crossover experiment over a 12-week period to accomplish this

Recent data highlight average weight loss of over 24%, with significant reductions in total and visceral fat masssurpassing current GLP-1 options like Mounjaro and Wegovy

However, Januvia requires dose adjustment in patients with renal impairment specifically, a reduction to 50 mg for eGFR 3044 and 25 mg for eGFR below 30

It cannot prove how one person will respond

Association between renin-angiotensin system blockade discontinuation and all-cause mortality among persons with low estimated glomerular filtration rate