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MLN3897 Plus Methotrexate in Patients With Rheumatoid Arthritis: Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of an Oral CCR1 Antagonist in a Phase IIa, Double-Blind, Placebo-Controlled, Randomized, Proof-of-Concept Study

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7.3.2.1 Restoration of gut barrier integrity Probiotics have been shown to enhance the function of tight junction proteins, such as occludin and zonula occludens (ZO-1), which are crucial for maintaining intestinal epithelial integrity (Serek and Oleksy-Wawrzyniak, 2021)

After migrating out from the explants, the tendon fibroblasts began to grow rapidly

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