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Ferroptosis plays a crucial role in the pathological progression of osteosarcoma, and agents such as bavachin, TPZ, cisplatin, PEITC, and EF24 induce ferroptosis in osteosarcoma cells, thereby exerting therapeutic effects ( Table 1 )

If not eliminated by GPX4, the resultant accumulation of lipid peroxidation products drives ferroptosis

National and international authors have reported the rate of cleft lip to be approximately 3/10,000 lives birth