However, the activation of SIRT3 by dioscin inhibits AKT/FOXO1, increasing CPT1 levels to diminish lipid deposition
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Res.) to match the weight loss of GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 8 mice and n = 3-4 cages) for 14 days
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This reduction leads to an increase in reactive oxygen species (ROS) like hydroxyl radicals, hydrogen peroxide, and superoxide ions