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This is important because people with lupus nephritis are already at higher risk for kidney disease and cardiovascular disease

doi.org/10.3389/fendo.2023.1148556 Unfer V, Facchinetti F, Orr B, Giordani B, Nestler J

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Minoxidil's mechanism a systemic vasodilator with no follicle specificity means side effects can extend well beyond the scalp: unwanted facial hair, scalp irritation, contact dermatitis, and (in rare cases) cardiovascular changes from systemic absorption.6 GHK-Cu, as an endogenous peptide acting locally on the cells where it's applied, has no documented systemic side effects and no withdrawal phenomenon when discontinued

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