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Oral, intranasal, and transdermal formulations marketed for these molecules face severe bioavailability challenges

A patient may be a candidate for GLP-1 injections if they are struggling with weight loss, appetite control, overeating, cravings, obesity, or weight-related health concerns

Potential Serious Risks: While rare, GLP-1 drugs may increase risks for pancreatitis and kidney issues, emphasizing the need for vigilant patient monitoring

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In a 12-week trial of mecasermin rinfabate (IPLEX) in adults with ALS (N=330), symptomatic hypoglycaemia occurred in 6.8% of the active arm versus 2.4% of placebo [16]